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This creates an unformulated aqueous solution with no permeation enhancers, no mucoadhesive polymers, no pH optimization for nasal mucosa (optimal range roughly pH 4.5 to 6.5), and no validated spray characteristics

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Common reports include injection-site stinging, nausea, headache, flushing, and short-term fatigue

[DOI] [PMC free article] [PubMed] [Google Scholar] Midoux P., LeCam E., Coulaud D., Delain E

Liposomes are tiny, spherical vesicles that encapsulate the glutathione, protecting it from degradation in the digestive tract and enhancing its absorption into cells