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Causes : Chronic hepatitis B and C, cirrhosis, fatty liver disease, certain genetic conditions

Mitochondrial function in modulating human granulosa cell steroidogenesis and female fertility

While the pro-inflammatory effect of microcrystalline UA is well-established 3,20 , there are several indications that soluble UA free of UA crystals has protective effects against inflammatory mechanisms and toxicity 50 with effects on macrophage polarisation towards the anti-inflammatory M2 phenotype 51

Keir, S

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315,316 In UC, studies have shown that specific lncRNAs may be involved in the pathogenesis of the disease and that targeting them may be a valuable approach for treatment