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This early response is typically modest, serving as a sign that the compound is beginning to integrate with the body's internal processes

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[DOI] [PMC free article] [PubMed] [Google Scholar] 108.McAuley JL, Linden SK, Png CW, King RM, Pennington HL, Gendler SJ, Florin TH, Hill GR, Korolik V, McGuckin MA

A mild increase in nutrient signaling to mTORC1 in mice leads to parenchymal damage, myeloid inflammation and shortened lifespan