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In a case series that examined 32 men who were diagnosed with CP/CPPS according to the NIDDK classification and who were refractory to behavioral and pharmacological therapies, 41% (13 of 32) had Hunner lesion on cystoscopy

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Moreover, eltrombopag, a thrombopoietin receptor agonist approved for the treatment of idiopathic thrombocytopenic purpura and aplastic anemia, has also shown to be an efficient iron chelator, mobilizing iron and reducing ROS working synergistically with other iron chelators in vitro (160)

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Additionally, some people are predisposed to B12 deficiency as certain conditions exist where the body does not have the ability to absorb Vitamin B12 (Shipton & Thachil, 2015)