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Taken together, these findings suggest that GMSC-derived Schwann-like cells retained potent capabilities to promote pro-regenerative (M2) macrophage polarization while suppressing pro-inflammatory (M1) macrophage activation in crush-injured sciatic nerves of rats

This could result from the higher NADH production by Gdh2 as well as an upregulation of -oxidation

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The high-capacity pore pathway is permeable to molecules up to 10 angstroms () and is primarily controlled by claudin proteins