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The peptide's effects encompass: Psychological components: Increased sexual desire, fantasies, and motivation Physiological components: Enhanced genital arousal and lubrication in women, erectile responses in men Clinical Usage PT-141 gained FDA approval in June 2019 as Vyleesi for treatment of acquired, generalized HSDD in premenopausal women

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Because the peptide interacts with multiple receptor subtypes (MC1R, MC3R, MC4R, MC5R), it enables researchers to examine how receptor activation influences melanogenesis, appetite regulation, sexual function pathways, and energy balance in various experimental systems