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For example, in mitochondria, when the rate of acetyl group production exceeds the capacity of the Krebs cycle, CrAT activity is shifted to the production of acetylcarnitine to prevent depletion of the free CoA pool [151]

It was important to add sorbitol in control to match the osmolarity of high glucose diet

Conditions that predispose to accumulation of excess iron can be hereditary (e.g., hemochromatosis) or acquired (e.g., excess iron ingestion, chronic liver disease)

Tian FY, Everson TM, Lester B, Punshon T, Jackson BP, Hao K, et al

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PubMed+1 4 Safety and Metabolism of AOD9604, a Novel Nutraceutical Ingredient for Improved Metabolic Health J Endocrinol Metab, 2014