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Although primarily tested for renal disease, its NRF2-mediated mechanism suggests potential therapeutic applications for CVDs by reducing oxidative stress and inflammation in cardiac cells [217]

Edited by Professor Anastasis Stephanou Rights and permissions Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made

Following senescence induction by radiation, mitophagy becomes impaired

The collective findings from these studies highlight the critical role of ferroptosis in corneal injury and suggest that its inhibition could be beneficial for corneal preservation (152, 232)

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