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Compared with AF patients without thrombosis, AF patients with thrombosis had significantly increased circulating TMAO levels

Basically, its your internal clean-up crew

This pathway consists of two enzymes: aldose reductase and sorbitol dehydrogenase ( Figure 1 )

patients often experience redness (erythema), peeling or flaking of the skin, dryness, and a burning or stinging sensation, especially during the first few weeks of treatment