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Mechanisms that contribute to paclitaxel-induced neuropathy include immune-mediated processes, loss of peripheral fibers, demyelination and axon degeneration, altered retrograde and anterograde transport as well as mitochondrial dysfunction (Figure 4)

& Martinez, C

P., & Klaasen, C

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B vitamins : Supplementation with B vitamins has been shown to reduce levels of serum homocysteine, an amino acid associated with increased risk of cardiovascular and neurogenerative diseases and shown to be elevated in patients with obstructive sleep apnea

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