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We observed higher caspase-1/4/5 activity within the classical monocyte subset from COVID-19 patients when compared to HCs ( Figure 2B ), suggesting this cell subset contributes to IL-1 and IL-18 maturation during COVID-19

When the organism encounters internal or external stressorsbiological, physical, or chemicalthat disrupt cellular homeostasis, ROS production may exceed elimination capacity, resulting in ROS accumulation

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