does low glutathione cause autism The impact of metabolism in spectrum disorder An Open-Label Case Series of

Biomedicines 2023, 11, x FOR PEER REVIEW 2 of 20 In this review, we will assess what is currently known about the metabolism of GSH and its role in cell homeostasis, as well as its possible eects on cancer cells and on the ecacy of cancer treatments

*JAMA*, 281(15), 1415-1423

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Zhu et al., 2020

A combination of environmental insults in genetically predisposed individuals with or without low nephron endowment might result in the final common pathway of progressive CKD

This is accompanied by the upregulation of ER stress-related proteins, including PERK, IRE1, ATF4, CHOP, XBP-1 and ATF6