Therapeutic targeting of ERAD and ER stress in metabolic diseases 4-Phenylbutyric Acid (4-PBA) Chemical chaperones such as 4-PBA have demonstrated beneficial effects in mouse models of obesity and diabetes, normalizing hyperglycemia and restoring systemic insulin sensitivity
Additionally, the increased energy can help improve exercise performance and endurance
This peptide has also been seen to improve inflammation caused by conditions such as arthritis
Performance of M-DIRECT evaluation by RRV might need improvement Disclosure of interest: Nothing to disclose Poster Session II - PRE-HOSPITAL SERVICE ORGANISATION 09.00 - PRE-HOSPITAL SERVICE ORGANISATION - 09.01 - PRE-HOSPITAL SERVICE ORGANISATION P795 - ESOC25-295 REVALIDATION OF THE M-DIRECT SCALE IN PREHOSPITAL TRIAGE OF THROMBECTOMY CANDIDATES FOR DIRECT TRANSFER TO ENDOVASCULAR CENTER Jorge Rodriguez-Pardo 1 , Nicolas Riera-Lopez 2 , Elena de Celis Ruiz 1 , Roco Alonso-Castillo 1 , Andrea Higuera 1 , Carlos Gmez-Escalonilla 3 , Carlos Hervs Testal 1 , Laura Casado Fernndez 1 , Laura Gonzalez Martin 1 , Ricardo Rigual 1 , Manuel Lorenzo-Dieguez 1 , Carlos Estebas Armas 1 , Patricia Calleja Castao 4 , Joaquin Carneado-Ruiz 5 , Gerardo Ruiz-Ares 1 1 Neurology Department and Stroke Center
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