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doi: 10.1007/s10654-017-0255-x 25 BowdenJDel GrecoMFMinelliCDavey SmithGSheehanNAThompsonJR

The active ingredient in milk thistle is called silymarin

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Fe 3+ demonstrates a stronger binding affinity for -syn (131), potentially impacting -syn post-translational modifications or influencing Fe 2+ oxidation, thereby altering -syn fibril morphology and accelerating its aggregation (132)