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In terms of the role of the PPP in stem cell function, a number of studies have shown that loss of glucose-6-phosphate dehydrogenase (G6PD) increases mouse ESC susceptibility to oxidative stress-induced apoptosis, as well as effects their ability to undergo erythropoietic differentiation (Fico et al., 2004

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It will also be proposed that several of these different vicious circles may self-assemble in ways that facilitate disease perpetuation

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(3) various CLA isomers, and the exact molecular mechanisms by which CLAs positively influence oxidative stress, inflammation, body composition, and physical performance