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doi:10.1038/s41586-021-04282-9

Clinical Considerations Disease-associated maternal and/or embryo/fetal risk During pregnancy, visceral adipose tissue increases due to normal metabolic and hormonal changes

Step 1 Activity modification, medication & self-care Activity modification short-term avoidance of the postures and activities that aggravate symptoms (typically prolonged standing or walking long distances), combined with the postures that relieve them (sitting, leaning forward, riding a stationary bike)

Closer monitoring of HT at frequent intervals is important for earlier diagnosis of PTC

Therefore, attention is increasingly being devoted to the elucidation of the role that angiogenesis plays in the disruption of neuronal homeostasis and functions and in the subsequent development of brain diseases (Sharma and Brown 2021)

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