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In mammals, cobalamin is a cofactor for only two enzymes, methionine synthase and L-methylmalonyl-coenzyme A mutase (2)

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Marino, M., Pellegrini, M., Rosa, P

In addition, GRADE assessment, sensitivity tests, and subgroup analysis were used to assess quality of studies, detect publication bias and identify potential sources of heterogeneity among trials, respectively

The inflamed nerves can cause pain that may radiate down your leg(s)