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Nevertheless, the study fails to clarify differences in serum PCS levels among PBC patients at different disease stages, uses non-human primary Kupffer cells in vitro , and does not evaluate the safety threshold for clinical PCS supplementation, which limits its therapeutic translation

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For patients & payers: A step toward lower costs and broader access to proven obesity treatments For Teva Pharmaceuticals: A strategic move into one of the fastest-growing segments in global pharma For Novo Nordisk: Limited short-term impact, but mounting competitive pressure as generics gain ground This development could reshape affordability, accessibility, and competition in obesity care signaling the beginning of a new chapter for patients and healthcare systems worldwide