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Disruption of adenosine-5-phosphosulfate kinase in Arabidopsis reduces levels of sulfated secondary metabolites

Importantly, functional B12 deficiency can sometimes coexist with high total B12 levels, especially in kidney disease, and may require additional testing with methylmalonic acid (MMA) or holotranscobalamin if deficiency is suspected clinically

I., Mirica, S

MMR removes the base opposite to the adduct, which may cause a new mismatch, starting the pathway again and leading to the so-called futile cycle, generating double stranded breaks

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