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If GI symptoms are still significant at the end of a four-week block, the documented approach is to hold the current dose longer rather than escalate on schedule

Stanley et al

Cagrilintide is an amylin analogue that works through the amylin/calcitonin receptor system

Start with the pattern

Some patients report noticeable improvements in pain, mobility, and function within 2 to 4 weeks, while others can take up to 12 weeks or longer to see measurable progress

Baseline metabolic testing and hormone panels set a baseline, which should be regularly monitored, including glucose metrics, reproductive hormones, and ultrasound as appropriate