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Bae JH, Kim G

Ten nanomolar cells show up repeatedly as a working dose for collagen and growth experiments

Carnitine, a N-methylated amino acid, is responsible for transporting fatty acids across the inner mitochondrial membrane for beta-oxidation

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It demonstrates potent anti-glioblastoma activity by: (1) blocking tumor invasion and cytokinesis (inducing polyploidy), (2) disrupting mitochondrial dynamics to elevate ROS and trigger ferroptosis, and (3) sensitizing tumors to radiotherapy/kinase inhibitors via ROS-driven PDGFR/mTOR pathway activation

6.3.2 Therapeutic EVs in ovarian dysfunction: preclinical evidence 6.3.2.1 In vitro studies Evidence derived from in vitro ovarian models provides an important mechanistic framework supporting the feasibility of EVbased strategies for preclinical applications targeting ovarian aging and dysfunction