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Gene expression regulation mediated through reversible MA RNA methylation

The binding of IL-6 to its cell-surface receptor induces dimerization of the gp130

OkuboHSakodaHKushiyamaAFujishiroMNakatsuYFukushimaTet al

The choice of linker can significantly impact the efficacy and safety profile of ADCs

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A key reason lies in the robust excretory defense of hepatocytes and HCC cells: the MRP2 transporter efficiently pumps the newly formed MMA 3+ out of the cells, preventing its cytotoxic accumulation [8]