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Novo Nordisk submitted an NDA (new drug application) to the FDA on December 18, 2025, which is the formal step companies take when seeking approval for a medication to be marketed for public use

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WNT/-Catenin Signaling The WNT (Wingless integration site)/-catenin pathway is also involved in cell migration [101], and various WNT proteins help to stabilize the cytoskeleton and define cell polarity [102,103]