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Huster, D

Sleep architecture is assessed through patient history or, where available, actigraphy or polysomnography data specifically sleep latency, REM and slow-wave sleep proportions, and sleep fragmentation index

TMA syndromes require rapid intervention with plasmapheresis, immunosuppressive agents (corticosteroids), or complement-inhibiting therapies (e.g., eculizumab) due to their natural pathophysiology of endothelial damage and complement dysregulation

doi: 10.1161/CIRCRESAHA.116.304937 92 MaT.WangY

However, individualized plans, loading phases, and maintenance schedules may be tailored based on specific health needs and program requirements

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