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Consistent with their elevated SLC7A11 expression level, IRE1-null MDA-MB-231 cells also demonstrated increased cystine uptake, which can be inhibited by IRE1 reconstitution (Supplementary Fig

Symptoms of methemoglobinemia result from inadequate oxygen transport

Likewise, the peptide transporters (PepT) can be an alternative route to compensate for the inefficiency of colonocytes to uptake free amino acids

Erastin can interact with VDAC2 protein to trigger mitochondrial malfunction and oxidative substance release, eventually leading to oxidative cell death, i.e., ferroptosis (53) (Figure 1)

Neutrophil adaptations upon recruitment to the lung: new concepts and implications for homeostasis and disease

The association of elective hormone therapy with changes in lipids among glucose intolerant postmenopausal women in the Dabetes Prevention Program Metabolism 62 9: 1313-22