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If it is small it is usually of no consequence, but if it is large and involves a significant amount of the joint surface it may require surgery to fix the fragment and restore the joint surface

In addition, IDH1-dependent reductive glutamine metabolism produces NADPH, which decreases mitochondrial ROS during anchorage-independent growth 64

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The primary and secondary antibodies were diluted in a PBS solution containing 3% BSA, 1% horse serum, and 0.1% Triton X-100

Compare measured concentration to theoretical values