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The significant increase in m6A-modified genes may also lead to the conversion of microglia to the M1 phenotype and involvement in inflammatory responses (Li Q

If the drug does not readily cross lipid membranes, it will be confined mainly to the extracellular fluid and a plasma sample therefore will have a high drug concentration

Cell counting Astrocytes grown in 6 cm dishes were harvested by applying trypsin-EDTA (Gibco) and the collected cells were centrifuged at 1,000 rpm for 5 min

miR-93 agomir reduces cytokine expression, microglial activation, inflammation, and RGCs loss, by targeting STAT3 to exert its effect on RGC death (Wang et al., 2021)