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When the liver is damaged, excess copper then accumulates in the brain, kidneys, joints, heart and eyes

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PMID 15064724

These include: Some serious side effects may occur with Humira that require immediate medical attention, including: hives itching tingling or numbness chest pain pale skin difficulty swallowing difficulty breathing weakness in legs vision problems shortness of breath rash joint pain fever, chills, or other signs of infection swelling in the ankles, feet, legs, or face Humira can also increase the chances of developing skin cancer, lymphoma, and other types of cancer