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Tumor necrosis factor-alpha (TNF-alpha), a cytokine involved in systemic inflammation, along with matrix metalloproteinase-2 (MMP-2) and matrix metalloproteinase-9 (MMP-9) enzymes that break down extracellular matrix proteins might potentially influence both the inflammatory processes and the remodeling of tissues

Dermal fillers use substances like hyaluronic acid or calcium hydroxyapatite to add volume and hydrate the skin

In studies examining blood GSH in AD, most studies did not examine potential vascular contributions

In lesioning surgery techniques (pallidotomy and thalamotomy), a small lesion is created in the targeted areas of the brain to disrupt abnormal brain activity (68)

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Subsequent research must further clarify the role of the MGBA axis across varying malignancies, radiation site, and dose parameters (Li et al., 2022)