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Naturally occurring human anti-band 3 autoantibodies accelerate clearance of erythrocytes in guinea pigs

In this context, NQO1-mediated suppression of TBK1 signaling may represent a protective feedback mechanism to restrain excessive inflammation

However, there is no FDA-approved indication for this use

Although the heritability of AD is high, knowledge of the disease-associated genes and their expression regulation still remains limited

210 In addition, oligonucleotide-based gene therapy using miR mimic or agomiR, noncoding RNA inhibitors (antisense oligonucleotides, locked nucleic acid, antagomiR), small interfering RNA, and modified RNA, has also been applied to regulate gene expressions in vivo

Zhang Z, Wang J, Zhang R, Huang R (2012) The ethylene response factor AtERF98 enhances tolerance to salt through the transcriptional activation of ascorbic acid synthesis in Arabidopsis