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This release can occur through different mechanisms, such as nanoparticle dissolutionan instability that arises under specific pH conditions, typically at lower pH, leading to matrix dissolutionand polymer swelling, a process in which nanoparticles swell at certain pH conditions, both ultimately resulting in drug release (Karimi et al., 2016)

doi: 10.15252/embj.2019101982 85 WaaijerMECGunnDAAdamsPDPawlikowskiJSGriffithsCEMvan HeemstDet al

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IV drips allow clinicians to monitor the infusion and adjust dosing with more precision

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The latter can trigger septic shock