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Over time, complications such as skin discoloration, swelling, leg pain, itching, and chronic venous insufficiency may occur

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Furthermore, the microenvironment protects MM cells to CD38 antibody-induced ADCC by upregulation of anti-apoptotic molecules, such as survivin

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These compounds exhibit a wide range of pharmacological effects, such as anti-inflammatory, antioxidative, anticancer, and vasodilatory activities, making ginger a valuable natural remedy in traditional and modern medicine [150,151,152]