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Despite advancements in analytical techniques, 492 including copper isotope measurement 493 and chemical fluorescent probes, 494 their application in cuproptosis-related research remains largely confined to cell lines or in vitro tissues

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Leptin is also recognized as a pro-inflammatory cytokine [5], demonstrating inflammatory characteristics comparable to other acute-phase reactants through the enhancement of secretion for multiple inflammatory cytokines, encompassing TNF-, IL-6, and IL-1