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Acutely elevated serum NfL levels reflect the level of axonal damage in early disease and are elevated in both the axonal and demyelinating NCS subtypes, indicating varying degrees of axonal involvement, even in those patients with a primarily demyelinating presentation (45)

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doi: 10.1038/s41580-020-0218-z 240 TepestR.VogeleyK.ViebahnB.Schneider-AxmannT.HonerW

Its structure is similar to that of the LDL particle