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This includes people with: Pernicious anaemia (autoimmune destruction of intrinsic factor-producing cells), typically requiring lifelong IM injections Crohn's disease or surgical resection affecting the terminal ileum Coeliac disease causing malabsorption (may improve with gluten-free diet) Chronic pancreatitis reducing enzyme availability needed for B12 release Vegans and strict vegetarians need reliable B12 sources through fortified foods or supplements, as plant-based diets contain negligible amounts of active B12

Thus, taking adequate levels of vitamin B12 and folate is necessary to produce and regulate essential neurotransmitters, thereby supporting optimal cognitive function

Pregnancy and Breastfeeding: Pregnant and breastfeeding women have increased vitamin B12 requirements to support the growth and development of the fetus or infant

To view a copy of this licence, visit About this article Cite this article Campos-Pardos, E., Uranga, S., Pic, A

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But if left untreated, it may cause the following symptoms: Weakness, tiredness, or lightheadedness Lack of energy A decline in your mental abilities, such as memory and focus A painful and red tongue (glossitis) Mouth ulcers Pins and needles (paraesthesia) Disturbed vision Irritability Causes of Vitamin B12 deficiency