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Fewer reconstitution events per protocol cycle

For example, the addition of semaglutide at a dose of 0.5 mg or 1 mg per week in patients receiving basal insulin resulted in a 1% and 1.8% decrease in HbA1c, respectively, in SUSTAIN- 5

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Restoration of altered endogenous neurosteroid levels via modulation of steroidogenesis mediated by pregnane xenobiotic receptors (PXR) and the endocannabinoid system has been suggested as an alternative to direct administration of neurosteroids (178, 337)