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Ethical approval for the study was obtained from the Faculty of Dentistry, Universiti Malaya [Reference no

Twenty-seven patients did not undergo HBOT due to outside of the treatment window or patients declined HBOT

doi 10.1016/j.ebiom.2015.07.007

It is considered the master anti-oxidant, increases energy, slows down the ageing process, detoxifies the liver and improves the skin

GPX1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated

Excessive ROS accumulation would disrupt the stable state of cells, not only causing oxidative stress, but also promoting the activation of autophagy (Bensaad et al., 2009)