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Chen Y, Shertzer HG, Schneider SN, Nebert DW, Dalton TP (2005) Glutamate cysteine ligase catalysis: dependence on ATP and modifier subunit for regulation of tissue glutathione levels

In contrast to strep-MBP-ROXY9, which quantitatively stayed in the reduced form in the presence of GSH, incubation of strep-MBP-GRXC2 with GSH already led to the formation of two oxidized species (Fig