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Eliminate oxidative stress Mitochondrial dynamics, which include ROS generation, autophagy, and cell apoptosis, are closely linked to the pathophysiology of ischemic stroke

PloS Biol (2018) 16(5):e2006203

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Therefore, combining metabolic therapy with immune checkpoint inhibitors by enhancing immune cell energy metabolism, reducing mitochondrial dysfunction and mtROS production in immune cells, and increasing the survival of effector T cells and the generation of memory T cells is a novel strategy to control tumor growth

Dollet, L

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