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Psychoneuroendocrinology 36 , 15301539 (2011)

Use generic antioxidants only after defining the redox phenotype (biomarkers + target compartments) and prioritize targeted (e.g., mitochondrial) or time-staged formulations (acute/subacute windows)

Additionally, CD38 expression on MM cells decreases rapidly during daratumumab treatment, is markedly reduced at time of progression, and may take up to 6 months to rebound after stopping daratumumab [35]