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The safety of hydrochlorothiazide and triamterene administration during pregnancy has not been established, so the combination product should be administered to pregnant women only when absolutely necessary (the potential benefits to the mother significantly outweigh the potential risk to the fetus)

The dyschromia presents with depigmented macules, due to loss of melanocytes from the cutaneous epidermis or loss of the ability to secrete melanin

Risk of anemia with metformin use in type 2 diabetes: a MASTERMIND study

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