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There are several proposed etiologies for development of this condition, however much debate still remains for the exact pathophysiology

Medications administered by subcutaneous injection include those that can be given in small volumes

This metabolic shift is evident in DCs in vivo , in response to poly(I:C)-stimulated type I IFN signaling 11

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However, this is typically a last resort and is reserved for individuals who have serious complications and have not responded to other treatments

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