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Therefore, no dose adjustment is required in patients with creatinine clearance greater than or equal to 35 mL/min [see Contraindications (4), Warnings and Precautions (5.3)]

MRI, metabolic screening, and genetic testing should be performed as soon as possible in patients with infantile seizures to establish an early diagnosis and prevent neurologic sequelae with timely and effective treatment [79]

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This also can be applied to the healing of anastomoses, as evidenced by the simultaneous healing of both stumps of the anastomosis (i.e., various gastrointestinal anastomoses (Sikiric et al., 1993