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Serum ceruloplasmin levels were assessed using immunonephelometry with the Beckman Coulter Immage 800 and standard reagents (Beckman Coulter, Brea, CA, USA)

Remember, B12 deficiency can cause a whole host of symptoms, and reversing those effects might take some time

Although this is a necessary first step in biomedical development, it is also a sign that R&D for these conditions operates in a somewhat rigged race, starting off with and slowed down by a lack of funding and available medical knowledge from the outset

So, instead of high B12 blood levels leading to cancer, maybe cancer leads to high blood levels of B12

Maintenance at 2.4 mg/week: 20 mg pen for 89 weeks, 10 mg pen for 4 weeks

However, Suzuki et al 174 found that strong ALDH1A1 expression was associated with better tumor differentiation and had little correlation with stem cell characteristics in HCC cells