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Another limitation was that both studies had low numbers of participants, with the fewest in the groups with severe renal or hepatic impairment

[DOI] [PubMed] [Google Scholar] 141.Roberfroid M, Gibson GR, Hoyles L, McCartney AL, Rastall R, Rowland I, Wolvers D, Watzl B, Szajewska H, Stahl B, Guarner F, Respondek F, Whelan K, Coxam V, Davicco M-J, Lotoing L, Wittrant Y, Delzenne NM, Cani PD, Neyrinck AM, Meheust A

The resistance index (RI) in cisplatin-resistant cells was reduced from 4.2 to 1.8 following combination therapy, while vincristine-resistant cells showed a decrease in RI from 3.7 to 2.1