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Wrangle et al., 2018), and increased cytotoxic T cell expansion (NCT01885897) (Romee et al., 2018

Also, misplacement of recombinant gene therapy products has been associated with lower extremity paralysis after intradural injection, and with paraesthesia, systemic illness, and death after epidural injection [94, 95]

On the other hand, they induce slow (hundreds of milliseconds) and sustained activity primarily through G i/o proteins by triggering signal transduction pathways and activating downstream effectors such as ion channels and adenylate cyclase

Adnan SB, Maarof M, Fauzi MB, Md Fadilah NI