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This acylcarnitine is transported into the mitochondrial matrix via the carnitine-acylcarnitine translocase, and then it gets transformed back into acyl-CoA by CPT2 on the matrix side (Kotlyarov 2022)

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These results suggested that responsive CRPCs exhibit a distinct AR cistrome and differential biological role of the AR compared to CRPCs with innate resistance that could be exploited for the development of a predictive biomarker [65]

Urinary concentrations of the -oxidation metabolites of VPA were low, whereas concentrations of -oxidation metabolites were high

J Clin Endocrinol Metab (2000) 85(7):240210

When combined with the reduced food intake from tirzepatide, carnitine levels could drop below optimal thresholds for efficient fat metabolism