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It has been chemically modified to remove the ability to stimulate bone marrow (which makes red blood cells) while retaining the ability to activate tissue repair

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Ibuprofen (1.5 M) or 3-PLG-ibu and 3-PLG-ibu-A-GSH nanocarriers (100 g/ml) were added as co-treatments

While substantial progress has been made in understanding these effects, critical gaps remain in mixture toxicology, low-dose effects, and transgenerational impacts in humans