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Two key regulators of mitochondrial biogenesis, namely, proliferator-activated receptor gamma coactivator 1- and nuclear respiratory factor 1, which are responsible for mitochondrial DNA transcription, are under the control of Nrf2 (Piantadosi et al., 2008

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Further, AA147 upregulated both the NRF2-selective ARE-LUC reporter ( Fig

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Hawkins CL, Davies MJ (2019) Detection, identification, and quantification of oxidative protein modifications