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*Correspondence: Ahmad H

Cancer-cell-secreted Exosomal miR-105 promotes tumour growth through the MYC-dependent metabolic reprogramming of stromal cells

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Targeting hypoxia in the tumor microenvironment: a potential strategy to improve cancer immunotherapy

While current research has shown some efficacy of SHMT inhibitors in cancer treatment, the fact that SHMT inhibitors target a central metabolic enzyme present in both normal and tumor cells means that potential toxicity remains one of the greatest challenges on the path to clinical translation